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PROTAC FGFR1 degrader-1

CAT: 0013-GTR19249096-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19249096-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC FGFR1 degrader-1 (S2H) is a bifunctional molecule that potently degrades FGFR1, with an IC50 of 26.81 nM and a DC50 of 39.78 nM in KG1a cells. It is composed of a pomalidomide-based E3 ligase ligand linked to an FGFR1-targeting warhead via a 9-bromononanoic acid linker, useful for studying targeted protein degradation in cancer research models.
Field of Research
Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction
Molecular Formula
C46H54N8O8
Molecular Weight
846.97
Storage Conditions
-20°C
Notes
For research use only.

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