PROTAC tubulin-Degrader-1

PROTAC tubulin-Degrader-1

• UNSPSC Description: PROTAC tubulin-IN-1 (compound W13) is an inhibitor of PROTAC tubulin. PROTAC tubulin-IN-1 exhibits antitumor activity against human lung cancer[1].
• Target Antigen: Microtubule/Tubulin
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/protac-tubulin-degrader-1.html
• Solubility: 10 mM in DMSO
• Smiles: COC1=C(OC)C(OC)=CC(/C=C\C2=CC=C(OC)C(OC(CCCN3C(CCC(N4C(C(C(N)=CC=C5)=C5C4=O)=O)C3=O)=O)=O)=C2)=C1
• Molecular Weight: 657.67
• References & Citations: [1]Yang H, et al.Discovery of the cereblon-recruiting tubulin PROTACs effective in overcoming Taxol resistance in vitro and in vivo. Eur J Med Chem. 2023 Dec 27;265:116067.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported