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PROTAC NCOA4 degrader-1

CAT: 0013-GTR19238063-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19238063-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTACNCOA4 degrader-1 (V3) is a potent, cell-permeable PROTAC inducing NCOA4 degradation with a DC50 of 3 nM in HeLa cells. It functions as a ferroptosis inhibitor by reducing NCOA4 and intracellular Fe2+, and has demonstrated protective efficacy in a CCl4-induced acute liver injury model in vivo.
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Storage Conditions
-20°C
Notes
For research use only.

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