EGFR-IN-2

CAT: 0013-GTR19205967-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0013-GTR19205967-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

EGFR-IN-2 is an orally bioavailable, mutation-selective EGFR inhibitor designed for NSCLC research. It potently targets T790M resistance mutants (IC50 27-33 nM) while sparing wild-type EGFR (IC50 218 nM) . This profile supports its investigation in preclinical models for overcoming tyrosine kinase inhibitor resistance.

CAS Number

1643497-70-4

Product Name Alternative

EGFRIN2, EGFR, EGFR IN 2

Field of Research

Cardiovascular Research, Cell Biology, Signal Transduction

Purity

98.52% (May vary between batches)

Smiles

[C@@H] (CC) (C) N1N=C (C=2C1=CC (NC3=NC (=NC=C3) C4=CN (S (=O) (=O) C5CC5) N=C4) =NC2) N6CC (C (C) (C) O) C6

Molecular Formula

C26H33N9O3S

Molecular Weight

551.66

Storage Conditions

-20°C

Notes

For research use only.

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GTR19185808-01	EGFR/HER2-IN-2
GTR19235428-01	EGFR mutant-IN-2
GTR19230874-01	EGFR/BRAFV600E-IN-2
GTR19230316-01	EGFR/CDK2-IN-2
GTR19273016-01	EGFR/HDAC-IN-2
GTR19220881-01	EGFR T790M/L858R-IN-2
GTR19217564-01	EGFR/HER2/DHFR-IN-2

Alternative Products

Catalog	Name
HY-100520-01	EGFR-IN-2
T209533-01	EGFR-TK-IN-2
T200843-01	SOS1/EGFR-IN-2
HY-168170	EGFR/VEGFR2-IN-2
HY-128860	Mutated EGFR-IN-2
T86344-01	EGFR mutant-IN-2
HY-150905	EGFR ligand-2
T79727-01	EGFR/CDK2-IN-2
MBS5820510	EGFR/BRAFV600E-IN-2
MBS5821055	ALK/EGFR-IN-2

EGFR-IN-2

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