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EGFR mutant-IN-2

CAT: 0013-GTR19235428-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19235428-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR mutant-IN-2 (D51) is a potent, selective inhibitor of EGFR triple mutants L858R/T790M/C797S and del19/T790M/C797S, with IC50 values of 14 nM and 62 nM, respectively. It demonstrates favorable pharmacokinetics, safety, and in vivo stability, supporting its use in preclinical research for studying resistant non-small cell lung cancer (NSCLC) models both in vitro and in vivo.
CAS Number
2770009-06-6
Field of Research
Cardiovascular Research, Cell Biology, Signal Transduction
Smiles
C (F) (F) (F) C=1C (C=2C=3C (N (S (CC) (=O) =O) C2) =CC=CC3) =NC (NC=4C=C5C (=CC4) N (CCN (C) C) C=C5) =NC1
Molecular Formula
C27H27F3N6O2S
Molecular Weight
556.6
Storage Conditions
-20°C
Notes
For research use only.

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