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EGFR/DHFR-IN-2

CAT: 0013-GTR19257833-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19257833-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
EGFR/DHFR-IN-2 (9b) is a dual inhibitor of h-DHFR/EGFR TK, exhibiting IC50 values of 0.192 μM for h-DHFR and 0.109 μM for EGFR. It causes cell cycle arrest at the G1/S phase and induces apoptosis. Additionally, EGFR/DHFR-IN-2 (9b) is a potential inhibitor of CYP2C9 and CYP3A4. This compound can be utilized in cancer research.
Field of Research
Cardiovascular Research, Cell Biology, Metabolism Research, Metabolism Research; Cell Biology, Molecular Biology, Signal Transduction
Molecular Formula
C24H16N4O5
Storage Conditions
-20°C
Notes
For research use only.

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