Products for Research Use Only
RegisterLogin

KT-5823

CAT: 0013-GTR19203700-02Size: 500 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19203700-02Size:500 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
KT5823
CAS Number
126643-37-6
Field of Research
Cell Biology, Epigenetics & Chromatin, Infectious Disease & Virology, Signal Transduction
Purity
>98%
Bioactivity
PKG inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) or in DMF (up to 20 mg/ml) .
Smiles
C[C@]12N3C=4C5=C (C6=C (C4C=7C3=CC=CC7) CN (C) C6=O) C=8C (N5[C@] (O1) (C[C@@]2 (C (OC) =O) OC) [H]) =CC=CC8
Molecular Formula
C29H25N3O5
Molecular Weight
495.5
Storage Conditions
-20°C
Notes
For research use only.

Chemical Information

Methyl (9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-9,12-epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylate

KT 5823 is an organic heterooctacyclic compound that is 1H,1'H-2,2'-biindole in which the nitrogens have undergone formal oxidative coupling to positions 2 and 5 of methyl (3R)-3-methoxy-2-methyltetrahydrofuran-3-carboxylate (the 2S,3R,5R product), and in which the 3 and 3' positions of the biindole moiety have also undergone formal oxidative coupling to positions 3 and 4 of 1-methyl-1,5-dihydro-2H-pyrrol-2-one. It has a role as an EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitor. It is a methyl ester, an organic heterooctacyclic compound, an indolocarbazole, a hemiaminal and a gamma-lactam.

CAS Number126643-37-6
PubChem CID108152
IUPAC Namemethyl (15S,16R,18R)-16-methoxy-4,15-dimethyl-3-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.115,18.02,6.07,27.08,13.019,26.020,25]octacosa-1,6,8,10,12,20,22,24,26-nonaene-16-carboxylate
Molecular FormulaC29H25N3O5
Molecular Weight495.5
XLogP3.5
Topological Polar Surface Area74.9
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Heavy Atom Count37
Formal Charge0
Complexity1020
SMILES
C[C@@]12[C@](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CN(C6=O)C)(C(=O)OC)OC
InChI
InChI=1S/C29H25N3O5/c1-28-29(36-4,27(34)35-3)13-20(37-28)31-18-11-7-5-9-15(18)22-23-17(14-30(2)26(23)33)21-16-10-6-8-12-19(16)32(28)25(21)24(22)31/h5-12,20H,13-14H2,1-4H3/t20-,28+,29+/m1/s1
InChIKey
QTYMDECKVKSGSM-YMUMJAELSA-N
Chemical Structure
2D Structure
2D structure of Methyl (9S,10R,12R)-2,3,9,10,11,12-hexahydro-10-methoxy-2,9-dimethyl-1-oxo-9,12-epoxy-1H-diindolo(1,2,3-fg:3',2',1'-kl)pyrrolo(3,4-i)(1,6)benzodiazocine-10-carboxylate
CAS: 126643-37-6
CID: 108152
Formula: C29H25N3O5
MW: 495.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight495.5
XLogP33.5
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass495.17942091
Monoisotopic Mass495.17942091
Topological Polar Surface Area74.9 Ų
Heavy Atom Count37
Formal Charge0
Complexity1020
Isotope Atom Count0
Defined Atom Stereocenter Count3
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19194400-01GW-5823
GTR19221258-01KT-474
GTR19233855-01KT-333
GTR19194097-01KT 1
GTR19203701-01KT-5720
GTR19250347-01KT-253
GTR19239274-01KT D606
GTR19236630KT-333
GTR19231426-01KT-531
GTR19197338-01KT-362 fumarate

Alternative Products

CatalogName
B6673-.1KT 5823
MBS515006-01KT-5823
TBI2083-100UGKT-5823, PKG inhibitor
A16021-0.1KT 5823 0.1mg
T32022-01GW-5823
6738/10KT 182
T200088-01KT D606
453071-01KT 5720
TRC-I627990-100MGIN-KT 319
MBS3600323KT-5720

Popular Products