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PHA-767491 hydrochloride

CAT: 0013-GTR19167937-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19167937-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PHA-767491 hydrochloride is a potent and selective ATP-competitive dual inhibitor of Cdc7 and CDK9 kinases, with IC50 values of 10 nM and 34 nM, respectively. It exhibits significant selectivity over related kinases and has been utilized in vitro and in vivo to study cell cycle progression, transcription, and oncology research.
CAS Number
942425-68-5
Product Name Alternative
Apoptosis, CAY 10572, CAY 10572 Hydrochloride, CAY10572, CAY-10572, CAY10572 HCl, CAY10572 Hydrochloride, CAY-10572 hydrochloride, Cdc7, Cdk9, CDK, Cdk1, Cdk2, GSK-3β, GSK3, PHA 767491, PHA767491, PHA-767491, PHA767491 HCl, PHA-767491 HCl, PHA-767491 Hydrochloride
Field of Research
Cell Biology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.00% (May vary between batches)
Solubility
DMSO:4.62 mg/mL (18.5 mM) ; H2O:25 mg/mL (100.12 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (4 mM)
Smiles
Cl.O=C1NCCc2[nH]c (cc12) -c1ccncc1
Molecular Formula
C12H12ClN3O
Molecular Weight
249.69
Storage Conditions
-20°C
Notes
For research use only.

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