Anti-hScrib | Protein LAP4

CAT: 0451-AS06 155Size: 100 µLDry Ice: NoHazardous: No

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CAT#:0451-AS06 155Size:100 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Scribble human homologue, hScrib, is a substrate of ubiquitin-mediated degradation by human papillomavirus E6 and the E6AP ubiquitin-protein ligase. hScrib is localised to the basolateral regions of the epithelial cell line MDCK. The mammalian homolog of Scribble has a primary structure and subcellular localization similar to that of its fly homolog, but its function remains unknown. hScrib can have a potential role in the suppression of mammalian tumorigenesis. Alternative name: Protein LAP4

CAS Number

9007-83-4

HS Code

38221900

Gene ID

23513

UniProt

Q14160

Host

Rabbit

Reactivity

Human

Not reactive in

No confirmed exceptions from predicted reactivity are currently known

Immunogen

GST tagged C-terminus of hScrib Q14160 including PDZ3 and 4 domains

Clonality

Polyclonal

Applications

Western blot (WB)

Field of Research

Other proteins

Dilution

1 : 5 000 (WB)

Purity

Serum

Format

Lyophilized

Reconstitution

For reconstitution add 100 µl of sterile water

Molecular Weight

175 kDa

Precautions

Reactivity showed on dilluted human cell culture extracts

Storage Conditions

Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Prediction Reactivity

Human

UniProtKB · Q14160

Protein scribble homolog

SCRIB_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q14160
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: SCRIB
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: Scribble, hScrib
EC number: —
Processing: —
Secondary accessions: Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell junctionCell membraneCell projectionCytoplasmMembraneSynapse

Domain

Coiled coilLeucine-rich repeatRepeat

Molecular function

Developmental protein

Biological process

Differentiation

Disease

Disease variant

PTM

LipoproteinPalmitatePhosphoproteinUbl conjugation

Product Datasheet

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Alternative Products

Catalog	Name
GTR17855748	HScrib \| Protein LAP4 Antibody
397545	SCRIB (Protein Scribble Homolog, Scribble, hScrib, Protein LAP4, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL)
MBS621189-01	Scribble (Scribbled homolog (Drosophila), CRIB1, hScrib, KIAA0147, LAP4, Protein LAP4, Protein scribble homolog, SCRB1, SCRIB1, Vartul, VARTUL)
041471	SCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4)
MBS6345425-01	SCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4) (PE)
MBS6345415-01	SCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4) (AP)
MBS6345418-01	SCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4) (FITC)
MBS6345417-01	SCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4) (Biotin)
MBS6345416-01	SCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4) (APC)
041471-AP	SCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4) (AP) discontinued