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HScrib | Protein LAP4 Antibody

CAT: 0013-GTR17855748Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0013-GTR17855748Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rabbit polyclonal antibody to hScrib | Protein LAP4
UniProt
Q14160
Reactivity
Human
Immunogen
GST tagged C-terminus of hScrib Q14160 including PDZ3 and 4 domains
Clonality
Polyclonal
Conjugation
Unconjugated
Field of Research
Cell Biology
Purification
Serum
Dilution
WB: 1: 5000
Form
Lyophilized
Molecular Weight
175 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Applications Notes
Scribble human homologue, hScrib, is a substrate of ubiquitin-mediated degradation by human papillomavirus E6 and the E6AP ubiquitin-protein ligase. hScrib is localised to the basolateral regions of the epithelial cell line MDCK. The mammalian homolog of Scribble has a primary structure and subcellular localization similar to that of its fly homolog, but its function remains unknown. hScrib can have a potential role in the suppression of mammalian tumorigenesis. Alternative name: Protein LAP4
Prediction Reactivity
Human
Tested Applications
WB
Host or Source
Rabbit

UniProtKB · Q14160

Protein scribble homolog

SCRIB_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q14160
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SCRIB
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Scribble, hScrib
EC number
—
Processing
—
Secondary accessions
Q6P496, Q7Z5D1, Q8WWV8, Q96C69, Q96GG1
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

Cell junctionCell membraneCell projectionCytoplasmMembraneSynapse

Domain

Coiled coilLeucine-rich repeatRepeat

Molecular function

Developmental protein

Biological process

Differentiation

Disease

Disease variant

PTM

LipoproteinPalmitatePhosphoproteinUbl conjugation

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Alternative Products

CatalogName
AS06 155Anti-hScrib | Protein LAP4
397545SCRIB (Protein Scribble Homolog, Scribble, hScrib, Protein LAP4, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL)
MBS621189-01Scribble (Scribbled homolog (Drosophila), CRIB1, hScrib, KIAA0147, LAP4, Protein LAP4, Protein scribble homolog, SCRB1, SCRIB1, Vartul, VARTUL)
041471SCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4)
MBS6345425-01SCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4) (PE)
MBS6345415-01SCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4) (AP)
MBS6345418-01SCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4) (FITC)
MBS6345417-01SCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4) (Biotin)
MBS6345416-01SCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4) (APC)
041471-APSCRIB, NT (SCRIB, CRIB1, KIAA0147, LAP4, SCRB1, VARTUL, Protein scribble homolog, Protein LAP4) (AP) discontinued

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