ALK5-IN-34

• UNSPSC Description:

  ALK5-IN-34 is an selective orally active activin receptor-like kinase (ALK) inhibitor. ALK5-IN-34 can inhibit the activity of ALK5-IN-34 with an IC50 value of ≤10 nM. ALK5-IN-34 also has inhibitory of tumor growth and can be used for the research of proliferative diseases, such as cancer[1].

• Target Antigen:

  TGF-beta/Smad; TGF-β Receptor

• Type:

  Reference compound

• Related Pathways:

  Stem Cell/Wnt;TGF-beta/Smad

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/alk5-in-34.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC1=CC=CC2=C(NC3=NC(NC4=CC=CC(N5CCOCC5)=C4)=NC=C3)C=NN=C12

• Molecular Weight:

  413.48

• References & Citations:

  [1]Bettina FRANZ, et al. Alk-5 inhibitors and uses thereof. Patent. WO2022126133A1.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2785430-90-0