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T-2307

CAT: 0804-HY-114220-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-114220-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
T-2307, an arylamidine, has antifungal activities in vitro and in vivo. T-2307 exhibits broad-spectrum activity against clinically significant pathogens, including Candida species (MIC range, 0.00025 to 0.0078 μg/ml), Cryptococcus neoformans (MIC range, 0.0039 to 0.0625 μg/ml), and Aspergillus species (MIC range, 0.0156 to 4 μg/mL) [1].
CAS Number
873546-31-7
Product Name Alternative
Acriflavinium (chloride) 3,6-Acridinediamine mix
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/t-2307.html
Purity
98.41
Solubility
1 M HCl : 12.5 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 50 mg/mL (ultrasonic; adjust pH to 3 with HCl)
Smiles
N=C(C1=CC=C(OCCCN2CCC(CCCOC3=CC=C(C(N)=N)C=C3)CC2)C=C1)N
Molecular Formula
C25H35N5O2
Molecular Weight
437.58
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Junichi Mitsuyama, et al. In vitro and in vivo antifungal activities of T-2307, a novel arylamidine. Antimicrob Agents Chemother. 2008 Apr;52 (4) :1318-24.|[2]Eio Yamada, et al. T-2307 shows efficacy in a murine model of Candida glabrata infection despite in vitro trailing growth phenomena. Antimicrob Agents Chemother. 2010 Sep;54 (9) :3630-4.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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