T 588

• Description :

  T 588 is an orally active neuroprotective agent. T 588 can increase acetylcholine release from the frontal cortex and hippocampus and meliorate cognitive dysfunction. T 588 can protect cerebellar granule cells from glutamate neurotoxicity. T 588can be used for the research of neurological disease, such as Alzheimer's disease[1].

• CAS Number :

  [142935-03-3]

• UNSPSC :

  12352005

• Target :

  NAChR

• Related Pathways :

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Smiles :

  CCN(CC)CCOC[C@@H](C1=CC=C(SC=C2)C2=C1)O.Cl

• Molecular Formula :

  C16H24ClNO2S

• Molecular Weight :

  329.89

• References & Citations :

  [1]Ikeda K, et al. T-588, a novel neuroprotective agent, delays progression of neuromuscular dysfunction in wobbler mouse motoneuron disease. Brain Res. 2000 Mar 6;858 (1) :84-91.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2