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T-1840383

CAT: 0804-HY-120661Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120661Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
T-1840383 is a potent, ATP-competitive inhibitor of c-Met/VEGFR-2, with the IC50s of 1.9 nM, 7.7 nM, 2.2 nM and 5.5 nM for c-Met, VEGFR1, VEGFR2 and VEGFR3, respectively[1].
CAS Number
1195779-24-8
UNSPSC
12352005
Target
C-Met/HGFR; VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/t-1840383.html
Smiles
O=C(NC1=CC=C(C(F)=C1)OC2=CN3C(C=C2)=NC(NC(C4CC4)=O)=C3)C5=CC=C(N(C5=O)C6=CC=CC=C6)C.Cl
Molecular Formula
C30H25ClFN5O4
Molecular Weight
574.00
References & Citations
[1]Z Yuan, et al. Advances on receptor tyrosine kinase inhibitors taking c-Met as anti-tumor target. Journal of China Pharmaceutical University.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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