Thioflavin T

CAT: 0804-HY-D0218-01Size: 500 mgDry Ice: NoHazardous: No
CAT#:0804-HY-D0218-01Size:500 mg
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Description
Thioflavin T is a cationic Benzothiazole dye that shows enhanced fluorescence upon binding to amyloid in tissue sections. Excitation max.: ~385 nm (free) ; ~450 nm (bound) ; Emission max.: ~445 nm (free) ; ~485 nm (bound) [1][2][3].
CAS Number
[2390-54-7]
Product Name Alternative
Basic Yellow 1
UNSPSC
12171500
Hazard Statement
H302, H315, H319, H335
Target
Amyloid-β
Type
Dye Reagents
Related Pathways
Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/Thioflavin_T.html
Purity
98.23
Solubility
DMSO : 16.67 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
CC1=CC=C2[N+](C)=C(C3=CC=C(N(C)C)C=C3)SC2=C1.[Cl-]
Molecular Formula
C17H19ClN2S
Molecular Weight
318.86
Precautions
H302, H315, H319, H335
References & Citations
[1]Khurana R, et al. Mechanism of thioflavin T binding to amyloid fibrils. J Struct Biol. 2005 Sep;151 (3) :229-38.|[2]Nakano H, et al. Globular-shaped Aβ oligomers have diverse mechanisms for promoting Aβ aggregations with the facilitation of fibril elongation. Neurobiol Dis. 2025 Feb;205:106775.|[3]Muramatsu D, et al. ALZ-801 prevents amyloid β-protein assembly and reduces cytotoxicity: A preclinical experimental study. FASEB J. 2025 Feb 15;39 (3) :e70382.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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