AM-2394

CAT: 0804-HY-100221-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-100221-01Size:5 mg
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AVAILABILITY: InStock
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Description
AM-2394 is a structurally distinct glucokinase activator (GKA) . AM-2394 activates glucokinase (GK) with an EC50 of 60 nM.
CAS Number
[1442684-77-6]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Glucokinase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/AM-2394.html
Purity
99.30
Solubility
DMSO : ≥ 30 mg/mL
Smiles
O=C(NC)NC1=CC(OC2=CC(C)=CN=C2)=C(C3=CC=C(OCC(C)(O)C)N=C3)C=N1
Molecular Formula
C22H25N5O4
Molecular Weight
423.47
Precautions
H302, H315, H319, H335
References & Citations
[1]Dransfield PJ, et al. Novel Series of Potent Glucokinase Activators Leading to the Discovery of AM-2394. ACS Med Chem Lett. 2016 May 23;7 (7) :714-8.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
526657AM-2394
441291-01AM 2394
A16331-2AM-2394 2mg
A16331-25AM-2394 25mg
A16331-100AM-2394 100mg
A16331-5AM-2394 5mg
A16331-10AM-2394 10mg
A16331-50AM-2394 50mg
A16331-10mM-DAM-2394 10mM * 1mL in DMSO
BA3382-5GDC-2394

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