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SCR-7952

CAT: 0804-HY-169257-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-169257-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SCR-7952 is a MAT2A inhibitor, with IC50 of 18.7 nM. SCR-7952 can be used in anti-cancer research[1].
CAS Number
2798856-04-7
UNSPSC
12352005
Target
Methionine Adenosyltransferase (MAT)
Type
Reference compound
Related Pathways
Epigenetics; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/scr-7952.html
Purity
99.77
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1N(C2=CC=CN=C2C3CC3)C4=C(C=CC(Cl)=C4)C5=C1N=CN5C
Molecular Formula
C19H15ClN4O
Molecular Weight
350.80
References & Citations
[1]Yu Z, et al. SCR-7952, a highly selective MAT2A inhibitor, demonstrates synergistic antitumor activities in combination with the S-adenosylmethionine-competitive or the methylthioadenosine-cooperative protein arginine methyltransferase 5 inhibitors in methylthioadenosine phosphorylase-deleted tumors. MedComm (2020) . 2024 Sep 20;5 (10) :e705.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported