Scr-IN-1

CAT: 0931-T205472-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T205472-01Size:10 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Apoptosis, Src

Related Pathways

Tyrosine Kinase/Adaptors, Apoptosis, Angiogenesis

Bioactivity

Scr-IN-1 (Compound 4e) is a tyrosine kinase inhibitor demonstrating inhibitory activity against HCT-116 and MIA-PaCa-2 cells, with IC50 values of 0.16 μM and 1.16 μM, respectively. It shows selectivity towards HCT-116 cells and MIA-PaCa-2 cells, with a selectivity index (SI) greater than 625 and 86. Scr-IN-1 induces apoptosis in HCT-116 colon cancer cells without altering the proportion of necrotic cells and is a potential novel SRC kinase inhibitor for HCT-116 cells. This compound is suitable for cancer research.

Molecular Formula

C26H16ClF3N2O3

Molecular Weight

496.87

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
HY-170958	Scr-IN-1
AA-4-01	Amyloid β (42- 1) SCR
HY-100458	SCR-4026
MBS5751773	SCR-1481B1
GTR19272870-01	Scr-IN-2
555635	SCR-1479
GTR17960346	SCR Antibody
MBS130820-01	SCR-7
GTR19239778-01	SCR-7952
HY-18711-01	SCR-1481B1 (free base)

Scr-IN-1

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