AC-7954

• UNSPSC Description:

  AC-7954 is a selective nonpeptidic urotensin receptor agonist (EC50: 300 nM at the human UII receptor)[1].

• Target Antigen:

  Urotensin Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/ac-7954.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ClC(C=C1)=CC=C1C(O2)(CCN(C)C)CC3=CC=CC=C3C2=O.Cl

• Molecular Weight:

  366.28

• References & Citations:

  [1]Croston GE, et al. Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3-(4-chlorophenyl)-3-(2- (dimethylamino)ethyl)isochroman-1-one (AC-7954). J Med Chem. 2002 Nov 7;45(23):4950-3.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  477313-09-0