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AC-7954

CAT: 0804-HY-10658-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-10658-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AC-7954 is a selective nonpeptidic urotensin receptor agonist (EC50: 300 nM at the human UII receptor) [1].
CAS Number
477313-09-0
UNSPSC
12352005
Target
Urotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ac-7954.html
Solubility
10 mM in DMSO
Smiles
ClC(C=C1)=CC=C1C(O2)(CCN(C)C)CC3=CC=CC=C3C2=O.Cl
Molecular Formula
C19H21Cl2NO2
Molecular Weight
366.28
References & Citations
[1]Croston GE, et al. Discovery of the first nonpeptide agonist of the GPR14/urotensin-II receptor: 3- (4-chlorophenyl) -3- (2- (dimethylamino) ethyl) isochroman-1-one (AC-7954) . J Med Chem. 2002 Nov 7;45 (23) :4950-3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported