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CC-3240

CAT: 0804-HY-163064-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-163064-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CC-3240 (compound 13) is a molecular glue degrader of CaMKK2 based on CC-8977, with the IC50 of 9 nM[1].
CAS Number
2922675-91-8
UNSPSC
12352005
Target
LRRK2; Molecular Glues
Type
Reference compound
Related Pathways
Autophagy; PROTAC
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cc-3240.html
Purity
98.23
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C3=C(C)N=CS3)C=C2)=O)[C@H](C(C)(C)C)NC(CCCCCCCCCOC4=CC5=C(C=C4)C(C6=CC(C7CCCC7)=C(C=C6)C(O)=O)=NC=N5)=O
Molecular Formula
C52H64N6O7S
Molecular Weight
917.17
References & Citations
[1]Chen Y, et al. Identification of Small Molecule Inhibitors and Ligand Directed Degraders of Calcium/Calmodulin Dependent Protein Kinase Kinase 1 and 2 (CaMKK1/2) . J Med Chem. 2023;66 (23) :15750-15760.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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