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RP-2119

CAT: 0804-HY-158346Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-158346Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RP-2119 (Compound 113) is an orally active inhibitor of Polymerase Theta (Polθ) . RP-2119 has antitumor activity[1].
CAS Number
2922287-81-6
UNSPSC
12352005
Target
DNA/RNA Synthesis
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/polθ-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=C(C=C(N=C1)C2=NN(C=C2)C)C3=CC(C(F)F)=NC=C3OC)NC4=NN=C(S4)C#CC5CC5
Molecular Formula
C24H19F2N7O2S
Molecular Weight
507.52
References & Citations
[1]Bingcan Liu, et al. N- (5-substituted-[ (l,3,4-thiadiazolyl) or (l,3-thiazolyl) ] (substituted) carboxamide compounds, pharmaceutical compositions, and methods of preparing the amide compounds and of their use. WO2024069592A1. 2024.04.04.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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A15239-100SLx-2119 100mg
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