Ethoxyquin dimer

• Description :

  Ethoxyquin dimer is a dimer of Ethoxyquin (HY-B1425) . Ethoxyquin dimer is an antioxidant. Ethoxyquin dimer can more readily accumulate in liver and adipose tissue compared with Ethoxyquin. Ethoxyquin above 10 mg/kg shows hepatotoxicity in mice[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Constitutive Androstane Receptor; Drug Metabolite; Keap1-Nrf2; Orphan Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/ethoxyquin-dimer.html

• Purity :

  98.70

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=CC(C)(C)NC2=C1C=C(OCC)C=C2N3C(C)(C)C=C(C)C4=C3C=CC(OCC)=C4

• Molecular Formula :

  C28H36N2O2

• Molecular Weight :

  432.60

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Bernhard A, et al. Subchronic dietary exposure to ethoxyquin dimer induces microvesicular steatosis in male BALB/c mice. Food Chem Toxicol. 2018 Aug;118:608-625.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [74681-77-9]