Ethoxyquin dimer

• Description:

  Ethoxyquin dimer is a dimer of Ethoxyquin (HY-B1425) . Ethoxyquin dimer is an antioxidant. Ethoxyquin dimer can more readily accumulate in liver and adipose tissue compared with Ethoxyquin. Ethoxyquin above 10 mg/kg shows hepatotoxicity in mice[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Constitutive Androstane Receptor; Drug Metabolite; Keap1-Nrf2; Orphan Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/ethoxyquin-dimer.html

• Purity:

  98.70

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=CC (C) (C) NC2=C1C=C (OCC) C=C2N3C (C) (C) C=C (C) C4=C3C=CC (OCC) =C4

• Molecular Formula:

  C28H36N2O2

• Molecular Weight:

  432.60

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Bernhard A, et al. Subchronic dietary exposure to ethoxyquin dimer induces microvesicular steatosis in male BALB/c mice. Food Chem Toxicol. 2018 Aug;118:608-625.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  74681-77-9