Ethoxyquin dimer

CAT: 0804-HY-138291Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-138291Size:1 mg
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Description
Ethoxyquin dimer is a dimer of Ethoxyquin (HY-B1425) . Ethoxyquin dimer is an antioxidant. Ethoxyquin dimer can more readily accumulate in liver and adipose tissue compared with Ethoxyquin. Ethoxyquin above 10 mg/kg shows hepatotoxicity in mice[1].
CAS Number
[74681-77-9]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Constitutive Androstane Receptor; Drug Metabolite; Keap1-Nrf2; Orphan Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ethoxyquin-dimer.html
Purity
98.70
Solubility
10 mM in DMSO
Smiles
CC1=CC(C)(C)NC2=C1C=C(OCC)C=C2N3C(C)(C)C=C(C)C4=C3C=CC(OCC)=C4
Molecular Formula
C28H36N2O2
Molecular Weight
432.60
Precautions
H302, H315, H319, H335
References & Citations
[1]Bernhard A, et al. Subchronic dietary exposure to ethoxyquin dimer induces microvesicular steatosis in male BALB/c mice. Food Chem Toxicol. 2018 Aug;118:608-625.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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