N-Acetyldopamine dimer-2

• Description:

  N-Acetyldopamine dimer-2 (compound 2) is a N-acetyldopamine dimer that can be isolated from the yellow powder form Periostracum Cicadae with antioxidant and anti-inflammatory activities. N-Acetyldopamine dimer-2 inhibits oxidized low-density lipoprotein (LDL) oxidation, ROS generation, NO production, and NF-κB activity[1].

• UNSPSC:

  12352005

• Target:

  NF-κB; Reactive Oxygen Species (ROS)

• Type:

  Natural Products

• Related Pathways:

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/n-acetyldopamine-dimer-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C=CC([C@H]1OC2=CC(/C=C/NC(C)=O)=CC=C2O[C@@H]1NC(C)=O)=C3)=C3O

• Molecular Formula:

  C20H20N2O6

• Molecular Weight:

  384.38

• References & Citations:

  [1]Xu MZ, et al. Antioxidant and anti-inflammatory activities of N-acetyldopamine dimers from Periostracum Cicadae. Bioorg Med Chem. 2006 Dec 1;14 (23) :7826-34.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  916888-49-8