BMS-986188

• UNSPSC Description:

  BMS-986188 is a selective positive allosteric modulator of δ-opioid receptor with an EC50 of 0.05 μM[1].

• Target Antigen:

  Opioid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/bms-986188.html

• Purity:

  99.06

• Solubility:

  DMSO : 62.5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  O=C1C2=C(CC(C)(C1)C)OC(CC(C)(CC3=O)C)=C3C2C4=CC=C(C=C4)OCC5=CC=CC=C5Br

• Molecular Weight:

  535.47

• References & Citations:

  [1]Burford NT, et al. Discovery, synthesis, and molecular pharmacology of selective positive allosteric modulators of the δ-opioid receptor. J Med Chem. 2015 May 28;58(10):4220-9.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  1776115-10-6