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2'-Hydroxychalcone

CAT: 0931-TN1163-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-TN1163-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1214-47-7
Target
Others, Autophagy, Antifungal, Apoptosis, NF-κB
Related Pathways
Apoptosis, Others, NF-κB, Microbiology/Virology, Autophagy
Purity
0.9854
Bioactivity
2'-Hydroxychalcone is a drug synthesis intermediate for the synthesis of flavonoids. 2'-Hydroxychalcone loaded in nanoemulsion showed fungicidal activity against Coccidioides parapsilosis in Danio rerio model.2'-Hydroxychalcone induced cytotoxicity through oxidative stress in lipid-loaded Hepg2 cells.2'-Hydroxychalcone inhibited the induction of ICAM-1, VCAM-α, tumor necrosis factor-α, and tumor necrosis factor-alpha as determined by reverse transcription-polymerase chain reaction determined by tumor necrosis factor-alpha induces steady-state transcript levels of ICAM-1, VCAM-1, and E-selectin, and therefore may interfere with the transcription of their genes.
Smiles
Oc1ccccc1C(=O)\C=C\c1ccccc1
Molecular Formula
C15H12O2
Molecular Weight
224.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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