Products for Research Use Only
RegisterLogin

2'-Hydroxychalcone

CAT: 0013-GTR19183654-01Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0013-GTR19183654-01Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
2'-Hydroxychalcone is a synthetic flavonoid intermediate with demonstrated bioactivity in research models. In vitro, it induces cytotoxicity via oxidative stress in HepG2 cells and inhibits pro-inflammatory adhesion molecule expression. In vivo, a nanoemulsion formulation has shown antifungal efficacy against Candida parapsilosis in a zebrafish (Danio rerio) model.
CAS Number
1214-47-7
Product Name Alternative
E-selectin, Fungal, ICAM-1, 1 (2 Hydroxyphenyl) 3 phenyl 2 propenone, 1 (2Hydroxyphenyl) 3phenyl2propenone, 2'-Hydroxychalcone, TNF-α, VCAM1
Field of Research
Cell Biology, Infectious Disease & Virology, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
DMSO:27.5 mg/mL (122.63 mM)
Smiles
Oc1ccccc1C (=O) \C=C\c1ccccc1
Molecular Formula
C15H12O2
Molecular Weight
224.25
Storage Conditions
Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.

Chemical Information

2'-Hydroxychalcone

2'-hydroxychalcone is a member of the class of chalcones that is trans-chalcone substituted by a hydroxy group at position 2'. It has a role as an anti-inflammatory agent. It is a member of chalcones and a member of phenols. It is functionally related to a trans-chalcone.

CAS Number1214-47-7
PubChem CID638276
IUPAC Name(E)-1-(2-hydroxyphenyl)-3-phenylprop-2-en-1-one
Molecular FormulaC15H12O2
Molecular Weight224.25
XLogP3.9
Topological Polar Surface Area37.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Heavy Atom Count17
Formal Charge0
Complexity277
SMILES
C1=CC=C(C=C1)/C=C/C(=O)C2=CC=CC=C2O
InChI
InChI=1S/C15H12O2/c16-14-9-5-4-8-13(14)15(17)11-10-12-6-2-1-3-7-12/h1-11,16H/b11-10+
InChIKey
AETKQQBRKSELEL-ZHACJKMWSA-N
Chemical Structure
2D Structure
2D structure of 2'-Hydroxychalcone
CAS: 1214-47-7
CID: 638276
Formula: C15H12O2
MW: 224.25
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight224.25
XLogP33.9
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count2
Rotatable Bond Count3
Exact Mass224.083729621
Monoisotopic Mass224.083729621
Topological Polar Surface Area37.3 Ų
Heavy Atom Count17
Formal Charge0
Complexity277
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
GTR19171121-014-Hydroxychalcone
GTR19167274-014'-Hydroxychalcone
GTR19216509-012,2,2-Trichloroethanol
GTR19255109-012,2,2-Trifluoroacetamide
GTR19170856-012,2,2-Trichloroethanol
GTR19216331-012-[2- (2,2,2-Trifluoroethoxy) phenoxy]ethyl methanesulfonate
GTR19228240-012-[2- (2,2,2-Trifluoroethoxy) phenoxy]ethyl bromide
GTR19166705-012-[2- (2,2,2-Trifluoroethoxy) phenoxy]ethyl methanesulfonate
GTR19243300-012,2-Dibromo-2-cyanoacetamide
GTR19169550-012,2':5',2''-Terthiophene

Alternative Products

CatalogName
HY-119931-012-Hydroxychalcone
TN1163-012'-Hydroxychalcone
HY-W012349-012′-Hydroxychalcone
FH66241-012'-Hydroxychalcone hydrazone
sc-206560(E) -2′-Hydroxychalcone
OR95849-01(E) -2-Hydroxychalcone
M37727-012-Hydroxychalcone B
sc-3569274'-Fluoro-2-hydroxychalcone
PC65355'-Fluoro-2'-hydroxychalcone
OR144192-Chloro-4'-hydroxychalcone

Popular Products