STING agonist-12

• Target:

  STING

• Related Pathways:

  Immunology/Inflammation

• Purity:

  0.9829

• Bioactivity:

  STING activator Compound 53 based on an oxindole core structure demonstrated robust on-target functional activation of STING (human EC50 185 nM) in immortalised and primary cells and a cytokine induction fingerprint consistent with STING activation.

• Smiles:

  CC1(C)C(=O)N(Cc2c(F)cccc2Cl)c2cc(ccc12)C(=O)NCc1c(F)cc(F)cc1F

• Molecular Formula:

  C25H19ClF4N2O2

• Molecular Weight:

  490.88

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2259624-71-8