Guanfu base A

CAT: 0931-T8182-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T8182-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1394-48-5

Target

Cytochromes P450, Potassium Channel

Related Pathways

Metabolism, Membrane transporter/Ion channel

Purity

0.9985

Bioactivity

Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 μM in HLMs; Ki: 0.37 μM for rCYP2D6) . It also inhibits HERG channel current.

Smiles

[H][C@@]12CC34CC(=C)[C@]5([H])[C@@H](O)[C@@]3([H])[C@@]36C[C@H](C[C@@](C)(CN1C3[C@@]4(O)[C@@H]5OC(C)=O)[C@@]26[H])OC(C)=O

Molecular Formula

C24H31NO6

Molecular Weight

429.5

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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