BDA-366

• Target :

  Bcl-2 Family

• Related Pathways :

  Apoptosis

• Purity :

  0.9946

• Bioactivity :

  BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its antiapoptotic function, thereby transforming it into a pro-apoptotic entity. This compound effectively suppresses lung cancer cell growth[1].

• Smiles :

  N(C[C@H]1CO1)C2=C3C(=C(NC[C@@H](CN(CC)CC)O)C=C2)C(=O)C=4C(C3=O)=CC=CC4

• Molecular Formula :

  C24H29N3O4

• Molecular Weight :

  423.5

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1909226-00-1