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APC 366

CAT: 0931-T22189-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T22189-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
158921-85-8
Target
Serine Protease, Serine/threonin kinase
Related Pathways
Proteases/Proteasome, Cell Cycle/Checkpoint, Metabolism
Purity
0.998
Bioactivity
APC 366 is a selective tryptase inhibitor (Ki = 7.1 μM) . Tryptase is a serine protease released during mast cell degranulation, which reduces acute airway responses to allergens and can be used for asthma allergy treatment.
Smiles
OC=1C2=C(C=CC1C(N[C@H](C(=O)N3[C@H](C(N)=O)CCC3)CCCNC(=N)N)=O)C=CC=C2
Molecular Formula
C22H28N6O4
Molecular Weight
440.5
Shipping Conditions
Ice Packs
Storage Temperature
-20°C