BDA-366

CAT: 0931-T6778-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T6778-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1909226-00-1
Target
Bcl-2 Family
Related Pathways
Apoptosis
Purity
0.9946
Bioactivity
BDA-366, a potent Bcl2 antagonist, selectively binds the Bcl2-BH4 domain with high affinity (Ki = 3.3 nM), inducing a conformational change that nullifies its antiapoptotic function, thereby transforming it into a pro-apoptotic entity. This compound effectively suppresses lung cancer cell growth[1].
Smiles
N(C[C@H]1CO1)C2=C3C(=C(NC[C@@H](CN(CC)CC)O)C=C2)C(=O)C=4C(C3=O)=CC=CC4
Molecular Formula
C24H29N3O4
Molecular Weight
423.5
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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