EGFR-IN-50

• CAS Number :

  2044508-48-5

• Target :

  Others|||EGFR

• Related Pathways :

  JAK/STAT signaling|||Tyrosine Kinase/Adaptors|||Others|||Angiogenesis

• Bioactivity :

  EGFR-IN-50 is a potent EGFR inhibitor targeting L858R resistance mutations, acting on TEL-EGFR-L858R-BaF3 and TEL-EGFR-T790M-L858R-BaF3 with GI50 values of 8 nM and 6.03 ?M, respectively. EGFR-IN-50 exhibits anti-proliferative effects on cancer cells. .

• Smiles :

  N(C=1C2=C(C=C(OCCCOC(CCSSCC=C)=O)C(OC)=C2)N=CN1)C3=CC(Br)=CC=C3

• Molecular Formula :

  C24H26BrN3O4S2

• Molecular Weight :

  564.51

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C