EGFR-IN-50

CAT: 0931-T63996-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T63996-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2044508-48-5

Target

Others, EGFR

Related Pathways

JAK/STAT signaling, Tyrosine Kinase/Adaptors, Others, Angiogenesis

Bioactivity

EGFR-IN-50 is a potent EGFR inhibitor targeting L858R resistance mutations, acting on TEL-EGFR-L858R-BaF3 and TEL-EGFR-T790M-L858R-BaF3 with GI50 values of 8 nM and 6.03 μM, respectively. EGFR-IN-50 exhibits anti-proliferative effects on cancer cells. .

Smiles

N(C=1C2=C(C=C(OCCCOC(CCSSCC=C)=O)C(OC)=C2)N=CN1)C3=CC(Br)=CC=C3

Molecular Formula

C24H26BrN3O4S2

Molecular Weight

564.51

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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EGFR-IN-50

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