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EGFR-IN-166

CAT: 0931-T211861-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211861-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
503443-98-9
Target
EGFR
Related Pathways
Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling
Bioactivity
EGFR-IN-166 (Compound 2) is an EGFR inhibitor demonstrating potent anticancer activity against breast cancer cells, with an IC50 of 69.63 μM for MCF-7 cells and 22.84 μM for MDA-MB-231 cells. It notably inhibits cell migration and EGFR expression, making it valuable for breast cancer research.
Smiles
O=C1SC(=C2C(=O)N(N=C2C)C=3C=CC=CC3)N(C=4C=CC=CC4)C1
Molecular Formula
C19H15N3O2S
Molecular Weight
349.41
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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