Products for Research Use Only

EGFR-IN-164

CAT: 0931-T211050-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211050-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
C-Kit, EGFR
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis
Bioactivity
EGFR-IN-164 (Compound 4) is a selective covalent allosteric inhibitor of EGFR. It effectively inhibits the activity of EGFR^L858R/T790M/C797S kinase with an IC50 of 48.1 nM and suppresses the proliferation of EGFR-mutant cells. EGFR-IN-164 is applicable in research focused on cancer resistance.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C