AMG-458

CAT: 0931-T6378-01Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-T6378-01Size:2 mg
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AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
913376-83-7
Target
C-Met/HGFR
Related Pathways
Tyrosine Kinase/Adaptors
Purity
0.9998
Bioactivity
AMG-458 is a potent c-Met inhibitor with Ki of 1.2 nM, ~350-fold selectivity for c-Met than VEGFR2 in cells.
Smiles
COc1ccc2c(Oc3ccc(NC(=O)c4c(C)n(CC(C)(C)O)n(-c5ccccc5)c4=O)nc3)ccnc2c1
Molecular Formula
C30H29N5O5
Molecular Weight
539.58
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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