Products for Research Use Only
RegisterLogin

OM-153

CAT: 0931-T63508-02Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T63508-02Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2406278-81-5
Target
PARP, Others, Wnt/beta-catenin
Related Pathways
Chromatin/Epigenetic, Others, DNA Damage/DNA Repair, Cytoskeletal Signaling, Stem Cells
Bioactivity
OM-153 is a potent inhibitor of tankyrase, acting on tankyrase 1 (IC50: 13 nM) and tankyrase 2 (IC50: 2 nM), and inhibiting WNT/β-linked protein signaling and proliferation in COLO 320DM.
Smiles
CCOc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2cccc3nccnc23)n1-c1ccccc1F
Molecular Formula
C28H24FN7O2
Molecular Weight
509.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

N-[3-[5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-1,2,4-triazol-3-yl]cyclobutyl]quinoxaline-5-carboxamide
CAS Number2406278-81-5
PubChem CID146282356
IUPAC NameN-[3-[5-(5-ethoxy-2-pyridinyl)-4-(2-fluorophenyl)-1,2,4-triazol-3-yl]cyclobutyl]quinoxaline-5-carboxamide
Molecular FormulaC28H24FN7O2
Molecular Weight509.5
XLogP3.1
Topological Polar Surface Area108
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Heavy Atom Count38
Formal Charge0
Complexity801
SMILES
CCOC1=CN=C(C=C1)C2=NN=C(N2C3=CC=CC=C3F)C4CC(C4)NC(=O)C5=C6C(=CC=C5)N=CC=N6
InChI
InChI=1S/C28H24FN7O2/c1-2-38-19-10-11-23(32-16-19)27-35-34-26(36(27)24-9-4-3-7-21(24)29)17-14-18(15-17)33-28(37)20-6-5-8-22-25(20)31-13-12-30-22/h3-13,16-18H,2,14-15H2,1H3,(H,33,37)
InChIKey
ARCOJIXZDJYBCH-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of N-[3-[5-(5-ethoxypyridin-2-yl)-4-(2-fluorophenyl)-1,2,4-triazol-3-yl]cyclobutyl]quinoxaline-5-carboxamide
CAS: 2406278-81-5
CID: 146282356
Formula: C28H24FN7O2
MW: 509.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight509.5
XLogP33.1
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count8
Rotatable Bond Count7
Exact Mass509.19755120
Monoisotopic Mass509.19755120
Topological Polar Surface Area108 Ų
Heavy Atom Count38
Formal Charge0
Complexity801
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T71367-01OM-4842
T71875-01OM-137
T62869-01OM-1700
T12301-01OM-189
T9901A-901-01OM-7D3-B3
T124003-01Antibiotic OM 173?2
TMPJ-00821-01OM Protein, Human, Recombinant (His)
TMPH-03344-01OM Protein, Rat, Recombinant (His)
T68911-01LAF-153
T40345AV-153

Alternative Products

CatalogName
BA4373-10OM-153
HY-145266OM-1700
MBS3844941-01OM-189
MBS5814380OM-137
MBS5813906OM-4842
HY-P991200-01OM-7D3-B3
A20496-50OM-189 50mg
A20496-10OM-189 10mg
A20496-5OM-189 5mg
A20496-1OM-189 1mg

Popular Products