AV-153

• Target:

  Others|||DNA/RNA Synthesis

• Related Pathways:

  Others|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

• Bioactivity:

  AV-153 is a 1,4-dihydropyridine derivative with antimutagenic properties. It intercalates into DNA at single strand breaks, resulting in reduced DNA damage and stimulation of DNA repair in human cells in vitro. AV-153 also interacts with thymine and cytosine and influences poly (ADP) ribosylation. Moreover, AV-153 exhibits anti-cancer activity.

• Smiles:

  [Na].CCOC (=O) C1=C (C) NC (C) =C (C1C (O) =O) C (=O) OCC |c:5,10|

• Molecular Formula:

  C14H19NNaO6

• Molecular Weight:

  320.297

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  27296-05-5