AV-153

• Target :

  Others|||DNA/RNA Synthesis

• Related Pathways :

  Others|||DNA Damage/DNA Repair|||Cell Cycle/Checkpoint

• Bioactivity :

  AV-153 is a 1,4-dihydropyridine derivative with antimutagenic properties. It intercalates into DNA at single strand breaks, resulting in reduced DNA damage and stimulation of DNA repair in human cells in vitro. AV-153 also interacts with thymine and cytosine and influences poly (ADP) ribosylation. Moreover, AV-153 exhibits anti-cancer activity.

• Smiles :

  [Na].CCOC(=O)C1=C(C)NC(C)=C(C1C(O)=O)C(=O)OCC|c:5,10|

• Molecular Formula :

  C14H19NNaO6

• Molecular Weight :

  320.297

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  27296-05-5