OM-1700

• Target :

  Others|||PARP

• Related Pathways :

  DNA Damage/DNA Repair|||Chromatin/Epigenetic|||Others

• Bioactivity :

  OM-1700 is a potent inhibitor of tankyrase, acting on tankyrase 1 (IC50: 127 nM) and tankyrase 2 (IC50: 14 nM) . OM-1700 inhibits the growth of colon cancer cell lines and inhibits COLO 320DM cells (GI50: 650 nM) .

• Smiles :

  FC1=C(N2C(=NN=C2C3=CC=C(OCC)C=N3)[C@@H]4C[C@@H](NC(=O)C5=CC=CC=N5)C4)C=CC=C1

• Molecular Formula :

  C25H23FN6O2

• Molecular Weight :

  458.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2406276-78-4