OM-153

• Target:

  PARP|||Others|||Wnt/beta-catenin

• Related Pathways:

  Chromatin/Epigenetic|||Others|||DNA Damage/DNA Repair|||Cytoskeletal Signaling|||Stem Cells

• Bioactivity:

  OM-153 is a potent inhibitor of tankyrase, acting on tankyrase 1 (IC50: 13 nM) and tankyrase 2 (IC50: 2 nM), and inhibiting WNT/?-linked protein signaling and proliferation in COLO 320DM.

• Smiles:

  CCOc1ccc(nc1)-c1nnc([C@H]2C[C@@H](C2)NC(=O)c2cccc3nccnc23)n1-c1ccccc1F

• Molecular Formula:

  C28H24FN7O2

• Molecular Weight:

  509.53

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2406278-81-5