OM-7D3-B3

• Description:

  OM-7D3-B3 is a monoclonal antibody targeting human claudin-1 (CLDN1) (Kd = 4 nM) . OM-7D3-B3 blocks the process in which CLDN1 is involved in the entry of hepatitis C virus (HCV) into cells. OM-7D3-B3 is promising for research of HCV infection[1][2].

• UNSPSC:

  12352203

• Target:

  Claudin; HCV

• Related Pathways:

  Anti-infection; Cytoskeleton

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Purity:

  97.98

• References & Citations:

  [1]Fofana I, et al. Monoclonal anti-claudin 1 antibodies prevent hepatitis C virus infection of primary human hepatocytes. Gastroenterology. 2010 Sep;139 (3) :953-64, 964.e1-4.|[2]Hashimoto Y, et al. Claudin-targeted drug development using anti-claudin monoclonal antibodies to treat hepatitis and cancer. Ann N Y Acad Sci. 2017 Jun;1397 (1) :5-16.

• Shipping Conditions:

  Dry Ice

• Storage Conditions:

  -80°C

• Scientific Category:

  Inhibitory Antibodies

• Clinical Information:

  No Development Reported

• Isoform:

  CLDN1