HCAIX-IN-8

• Target :

  Others|||Carbonic Anhydrase

• Related Pathways :

  Others|||Metabolism

• Bioactivity :

  HCAIX-IN-8 (compound 7i) is a highly potent and selective inhibitor of hCAIX with an IC50 value of 0.024 ?M, and also inhibits CAII and CAVA with IC50 values of 1.99 ?M and 1.10 ?M, respectively. It exhibits anti-proliferative effects, low toxicity, reduces epithelial-to-mesenchymal transitions, promotes apoptosis, and inhibits cell migration and colonization potential [1].

• Smiles :

  C(OC1=C(OC)C=C(/C=C/C(O)=O)C=C1)C2=CN(N=N2)C3=CC(N(=O)=O)=CC=C3

• Molecular Formula :

  C19H16N4O6

• Molecular Weight :

  396.35

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2414633-40-0