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Trk-IN-20

CAT: 0931-T61551-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61551-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2460924-63-2
Target
Trk receptor, Others
Related Pathways
Others, Tyrosine Kinase/Adaptors
Bioactivity
Trk-IN-20 is a 3-vinylindazole derivative compound that effectively inhibits the functions of Trk kinases. It accomplishes this by suppressing the phosphorylation of TrkA, TrkB, and TrkC, with IC50 values of 1.6 nM, 2.9 nM, and 2.0 nM, respectively [1].
Smiles
C(=C/C1=CC=CC=N1)\C=2C=3C(NN2)=CC=C(N[C@H](C)C4=CC(F)=CC(F)=C4)C3
Molecular Formula
C22H18F2N4
Molecular Weight
376.4
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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