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Trk-IN-9

CAT: 0931-T62806-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T62806-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2758623-12-8
Target
Apoptosis, Trk receptor
Related Pathways
Tyrosine Kinase/Adaptors, Apoptosis
Purity
0.9815
Bioactivity
Trk-IN-9 (Compound 12) is a potent inhibitor of TRK that inhibits the proliferation of Km-12 cell lines and induces apoptosis in a concentration-dependent manner. It also inhibits TRK phosphorylation and blocks downstream pathways, showing potential for NTRK fusion cancer research.
Smiles
N(C=1N=C(NCC2=CC(F)=CC=C2)C(Cl)=CN1)C3=CC(C(N[C@@H]4CCCNC4)=O)=CC=C3
Molecular Formula
C23H24ClFN6O
Molecular Weight
454.93
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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