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Hu7691 free base

CAT: 0931-T39733-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T39733-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2241232-43-7
Target
PKA, SGK, PKC, ROCK, Akt, S6 Kinase
Related Pathways
Stem Cells, Cytoskeletal Signaling, MAPK, Cell Cycle/Checkpoint, Metabolism, Tyrosine Kinase/Adaptors, Chromatin/Epigenetic, PI3K/Akt/mTOR signaling
Purity
0.9889
Bioactivity
Hu7691 free base is an orally active, potent, and selective Akt inhibitor with anti-proliferative and neurogenic effects on various neuroblastoma cell lines. It inhibits Akt1, Akt2, and Akt3, and induces differentiation of neuroblastoma cells.
Smiles
N(C(=O)C1=C(F)C=C(C=C1)C2=CC=NN2C)[C@H]3[C@@H](CCNC3)C4=CC(F)=C(F)C=C4
Molecular Formula
C22H21F3N4O
Molecular Weight
414.423
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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