γ-Amanitin

• Target:

  ADC Cytotoxin|||DNA/RNA Synthesis

• Related Pathways:

  Cell Cycle/Checkpoint|||Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair

• Bioactivity:

  ?-Amanitin, an ADC (antibody-drug conjugate) cytotoxin isolated from mushrooms, inhibits RNA polymerase II, disrupting mRNA synthesis. It exhibits effects akin to those of ?-Amanitin and ?-Amanitin.

• Smiles:

  CCC (C) C1NC (=O) CNC (=O) C2Cc3c ([nH]c4cc (O) ccc34) S (=O) CC (NC (=O) CNC1=O) C (=O) NC (CC (N) =O) C (=O) N1CC (O) CC1C (=O) NC (C (C) C (C) O) C (=O) N2

• Molecular Formula:

  C39H54N10O13S

• Molecular Weight:

  902.98

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  21150-23-2