Mal-C6-?-Amanitin

• Target:

  Drug-Linker Conjugates for ADC

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Bioactivity:

  Mal-C6-?-Amanitin, an ADC (antibody-drug conjugate) linker drug, incorporates the powerful antitumor agent ?-Amanitin, an inhibitor of RNA polymerase II, through the Mal-C6 linker, showcasing potent antitumor activity.

• Smiles:

  [H][C@@]12C[C@@H](O)CN1C(=O)[C@]([H])(CC(N)=O)NC(=O)[C@]1([H])CS(=O)c3[nH]c4cc(OCCCCCCNC(=O)CCCCCN5C(=O)C=CC5=O)ccc4c3C[C@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@@H](C)[C@@H](O)CO)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)CC)C(=O)NCC(=O)N1

• Molecular Formula:

  C55H78N12O17S

• Molecular Weight:

  1211.34

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1578249-76-9