β-Amanitin

• Target:

  DNA/RNA Synthesis|||ADC Cytotoxin

• Related Pathways:

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Antibody-drug Conjugate/ADC Related

• Bioactivity:

  ?-Amanitin, a cyclic peptide toxin found in the poisonous Amanita phalloides mushroom, inhibits eukaryotic RNA polymerase II and III, thereby disrupting protein synthesis.

• Smiles:

  [H][C@@]12C[C@@H](O)CN1C(=O)[C@]([H])(CC(O)=O)NC(=O)[C@]1([H])C[S@](=O)c3[nH]c4cc(O)ccc4c3C[C@]([H])(NC(=O)[C@@]([H])(NC2=O)[C@@H](C)[C@@H](O)CO)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)CC)C(=O)NCC(=O)N1

• Molecular Formula:

  C39H53N9O15S

• Molecular Weight:

  919.96

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  21150-22-1