γ-Amanitin

• Target :

  ADC Cytotoxin|||DNA/RNA Synthesis

• Related Pathways :

  Cell Cycle/Checkpoint|||Antibody-drug Conjugate/ADC Related|||DNA Damage/DNA Repair

• Bioactivity :

  ?-Amanitin, an ADC (antibody-drug conjugate) cytotoxin isolated from mushrooms, inhibits RNA polymerase II, disrupting mRNA synthesis. It exhibits effects akin to those of ?-Amanitin and ?-Amanitin.

• Smiles :

  CCC(C)C1NC(=O)CNC(=O)C2Cc3c([nH]c4cc(O)ccc34)S(=O)CC(NC(=O)CNC1=O)C(=O)NC(CC(N)=O)C(=O)N1CC(O)CC1C(=O)NC(C(C)C(C)O)C(=O)N2

• Molecular Formula :

  C39H54N10O13S

• Molecular Weight :

  902.98

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  21150-23-2