TMP-153

• Target :

  Acyltransferase

• Related Pathways :

  Metabolism

• Purity :

  0.9968

• Bioactivity :

  TMP-153 is a novel and potent ACAT inhibitor with an IC50 value of 5-10 nM for intestinal and hepatic ACAT in animals.TMP-153 has a hypocholesterolemic effect, inhibiting cholesterol uptake and lowering plasma cholesterol in rats and hamsters.

• Smiles :

  O=C(NC1=CC=C(F)C=C1F)NC2=CN=C3C=C(C(=CC3=C2C=4C=CC=CC4Cl)C)C

• Molecular Formula :

  C24H18ClF2N3O

• Molecular Weight :

  437.87

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  128831-46-9