TMP-153

• Target:

  Acyltransferase

• Related Pathways:

  Metabolism

• Purity:

  0.9968

• Bioactivity:

  TMP-153 is a novel and potent ACAT inhibitor with an IC50 value of 5-10 nM for intestinal and hepatic ACAT in animals.TMP-153 has a hypocholesterolemic effect, inhibiting cholesterol uptake and lowering plasma cholesterol in rats and hamsters.

• Smiles:

  O=C(NC1=CC=C(F)C=C1F)NC2=CN=C3C=C(C(=CC3=C2C=4C=CC=CC4Cl)C)C

• Molecular Formula:

  C24H18ClF2N3O

• Molecular Weight:

  437.87

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  128831-46-9