BS-153

CAT: 0931-T207422-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T207422-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1935692-54-8

Target

NF-κB

Related Pathways

NF-κB

Bioactivity

BS-153 is a novel synthetic oxazolidinone drug that exhibits anti-inflammatory effects by blocking the activation of the NF-κB/PKCθ pathway. It can suppress the expression levels of iNOS, COX-2, and pro-inflammatory cytokines (TNF-α, IL-1β, and IL-6) in LPS-stimulated RAW264.7 cells.

Smiles

N#CC1=CC(=CC=C1N2CCC(N3CCOCC3)CC2)C(=O)NC=4C=NN(C5=CC=C(Cl)C=C5)C4C(F)(F)F

Molecular Formula

C27H26ClF3N6O2

Molecular Weight

558.98

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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